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Access medicated weight loss treatment
At Tiara Clinics, we specialise in providing exceptional cosmetic services, including medicated weight loss solutions tailored to your needs. Our expert team offers injections and personalised advice to help you achieve your weight goals effectively. We understand that weight gain can be influenced by various factors such as genetics, lifestyle, and age, and we're here to support you on your journey. With a focus on combining lifestyle changes medical guidance, we aim to empower you to lead a healthier, happier life.
Welcome to your GLP-1 guide
Starting a new medication can feel overwhelming, but you don't have to navigate it alone. This guide was created to give you everything you need to feel informed and confident on your GLP-1 journey.
While many people think of medications like Wegovy and Mounjaro as new, the class of medication that they belong to were originally developed as a type 2 diabetes treatment. The first medication was FDA-approved in 2005 and licensed for use in the UK in 2007. Researchers discovered that these drugs not only helped regulate blood sugar but also led to significant weight loss. Over time, newer GLP-1 treatments like liraglutide (Saxenda) and semaglutide (Wegovy) were specifically approved for obesity management.
In clinical trials, patients taking tirzepatide (the active ingredient in Mounjaro) experienced weight loss of 20.9% after 72 weeks of treatment.
How GLP-1s work
GLP-1s work in the body by affecting multiple organs. They help to regulate appetite, metabolism, and fat storage.
This means that Mounjaro mimics two incretin hormones instead of just one. GIP also enhances insulin secretion after you eat and reduces appetite, which increases the effectiveness of Mounjaro.
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Appetite suppression: Your treatment activates receptors in parts of the brain called the hypothalamus and brainstem to reduce your appetite and increase feelings of fullness. It also works on the dopamine dependent systems in the brain, reducing the desire to snack by reducing the rewarding effects.
This helps to reduce “food noise” which is an informal term which describes the feeling of constant food-focused thoughts, such as what to eat, when to eat, and how much to eat.
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Slows digestion: Your medication slows down the rate at which food leaves your stomach, helping you stay fuller for longer.
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Blood sugar regulation: After eating, your treatment enhances insulin secretion from your pancreas, helping to control blood sugar levels. Mounjaro also increases insulin sensitivity, which means your cells can respond more effectively to insulin. When cells respond effectively to insulin, they efficiently take up glucose from the bloodstream and help to keep blood sugar levels within a healthy range to reduce cravings.
In clinical trials, patients taking semaglutide (the active ingredient in Wegovy) experienced weight loss of 14.9% in 68 weeks.
The science behind the medication
Clinically proven weight loss treatments target your metabolic patterns, helping you lose weight and keep it off.
Silence food noise
Targets the reward centre in your brain, so you’ll feel more satisfied after each meal and less likely to experience food focused thoughts.
Feel fuller for longer
Slows down the rate at which your stomach empties, helping to reduce your overall appetite.
Reduce cravings
Keeps your blood sugar level stable after eating, preventing spikes that can lead to increased hunger and cravings.